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Think U.S. health authorities have never conducted outrageous medical experiments on children, women, minorities, homosexuals and inmates? Think again: This timeline, originally put together by Dani Veracity (a NewsTarget reporter), has been edited and updated with recent vaccination experimentation programs in Maryland and New Jersey. Here's what's really happening in the United States when it comes to exploiting the public for medical experimentation:(1845 - 1849) J. Marion Sims, later hailed as the "father of gynecology," performs medical experiments on enslaved African women without anesthesia. These women would usually die of infection soon after surgery. Based on his belief that the movement of newborns' skull bones during protracted births causes trismus, he also uses a shoemaker's awl, a pointed tool shoemakers use to make holes in leather, to practice moving the skull bones of babies born to enslaved mothers (Brinker).(1895)New York pediatrician Henry Heiman infects a 4-year-old boy whom he calls "an idiot with chronic epilepsy" with gonorrhea as part of a medical experiment ("Human Experimentation: Before the Nazi Era and After").(1896)Dr. Arthur Wentworth turns 29 children at Boston's Children's Hospital into human guinea pigs when he performs spinal taps on them, just to test whether the procedure is harmful (Sharav).(1906)Harvard professor Dr. Richard Strong infects prisoners in the Philippines with cholera to study the disease; 13 of them die. He compensates survivors with cigars and cigarettes. During the Nuremberg Trials, Nazi doctors cite this study to justify their own medical experiments (Greger, Sharav).(1911)Dr. Hideyo Noguchi of the Rockefeller Institute for Medical Research publishes data on injecting an inactive syphilis preparation into the skin of 146 hospital patients and normal children in an attempt to develop a skin test for syphilis. Later, in 1913, several of these children's parents sue Dr. Noguchi for allegedly infecting their children with syphilis ("Reviews and Notes: History of Medicine: Subjected to Science: Human Experimentation in America before the Second World War").(1913)Medical experimenters "test" 15 children at the children's home St. Vincent's House in Philadelphia with tuberculin, resulting in permanent blindness in some of the children. Though the Pennsylvania House of Representatives records the incident, the researchers are not punished for the experiments ("Human Experimentation: Before the Nazi Era and After").(1915)Dr. Joseph Goldberger, under order of the U.S. Public Health Office, produces Pellagra, a debilitating disease that affects the central nervous system, in 12 Mississippi inmates to try to find a cure for the disease. One test subject later says that he had been through "a thousand hells." In 1935, after millions die from the disease, the director of the U.S Public Health Office would finally admit that officials had known that it was caused by a niacin deficiency for some time, but did nothing about it because it mostly affected poor African-Americans. During the Nuremberg Trials, Nazi doctors used this study to try to justify their medical experiments on concentration camp inmates (Greger; Cockburn and St. Clair, eds.).(1932)(1932-1972) The U.S. Public Health Service in Tuskegee, Ala. diagnoses 400 poor, black sharecroppers with syphilis but never tells them of their illness nor treats them; instead researchers use the men as human guinea pigs to follow the symptoms and progression of the disease. They all eventually die from syphilis and their families are never told that they could have been treated (Goliszek, University of Virginia Health System Health Sciences Library).(1939)In order to test his theory on the roots of stuttering, prominent speech pathologist Dr. Wendell Johnson performs his famous "Monster Experiment" on 22 children at the Iowa Soldiers' Orphans' Home in Davenport. Dr. Johnson and his graduate students put the children under intense psychological pressure, causing them to switch from speaking normally to stuttering heavily. At the time, some of the students reportedly warn Dr. Johnson that, "in the aftermath of World War II, observers might draw comparisons to Nazi experiments on human subjects, which could destroy his career" (Alliance for Human Research Protection).(1941)Dr. William C. Black infects a 12-month-old baby with herpes as part of a medical experiment. At the time, the editor of the Journal of Experimental Medicine, Francis Payton Rous, calls it "an abuse of power, an infringement of the rights of an individual, and not excusable because the illness which followed had implications for science" (Sharav).An article in a 1941 issue of Archives of Pediatrics describes medical studies of the severe gum disease Vincent's angina in which doctors transmit the disease from sick children to healthy children with oral swabs (Goliszek).Researchers give 800 poverty-stricken pregnant women at a Vanderbilt University prenatal clinic "cocktails" including radioactive iron in order to determine the iron requirements of pregnant women (Pacchioli).(1942)The Chemical Warfare Service begins mustard gas and lewisite experiments on 4,000 members of the U.S. military. Some test subjects don't realize they are volunteering for chemical exposure experiments, like 17-year-old Nathan Schnurman, who in 1944 thinks he is only volunteering to test "U.S. Navy summer clothes" (Goliszek).Merck Pharmaceuticals President George Merck is named director of the War Research Service (WRS), an agency designed to oversee the establishment of a biological warfare program (Goliszek).(1944 - 1946) A captain in the medical corps addresses an April 1944 memo to Col. Stanford Warren, head of the Manhattan Project's Medical Section, expressing his concerns about atom bomb component fluoride's central nervous system (CNS) effects and asking for animal research to be done to determine the extent of these effects: "Clinical evidence suggests that uranium hexafluoride may have a rather marked central nervous system effect ... It seems most likely that the F [code for fluoride] component rather than the T [code for uranium] is the causative factor ... Since work with these compounds is essential, it will be necessary to know in advance what mental effects may occur after exposure." The following year, the Manhattan Project would begin human-based studies on fluoride's effects (Griffiths and Bryson).The Manhattan Project medical team, led by the now infamous University of Rochester radiologist Col. Safford Warren, injects plutonium into patients at the University's teaching hospital, Strong Memorial (Burton Report).(1945)Continuing the Manhattan Project, researchers inject plutonium into three patients at the University of Chicago's Billings Hospital (Sharav).The U.S. State Department, Army intelligence and the CIA begin Operation Paperclip, offering Nazi scientists immunity and secret identities in exchange for work on top-secret government projects on aerodynamics and chemical warfare medicine in the United States ("Project Paperclip").(1945 - 1955) In Newburgh, N.Y., researchers linked to the Manhattan Project begin the most extensive American study ever done on the health effects of fluoridating public drinking water (Griffiths and Bryson).(1946)Continuing the Newburg study of 1945, the Manhattan Project commissions the University of Rochester to study fluoride's effects on animals and humans in a project codenamed "Program F." With the help of the New York State Health Department, Program F researchers secretly collect and analyze blood and tissue samples from Newburg residents. The studies are sponsored by the Atomic Energy Commission and take place at the University of Rochester Medical Center's Strong Memorial Hospital (Griffiths and Bryson).(1946 - 1947) University of Rochester researchers inject four male and two female human test subjects with uranium-234 and uranium-235 in dosages ranging from 6.4 to 70.7 micrograms per one kilogram of body weight in order to study how much uranium they could tolerate before their kidneys become damaged (Goliszek).Six male employees of a Chicago metallurgical laboratory are given water contaminated with plutonium-239 to drink so that researchers can learn how plutonium is absorbed into the digestive tract (Goliszek).Researchers begin using patients in VA hospitals as test subjects for human medical experiments, cleverly worded as "investigations" or "observations" in medical study reports to avoid negative connotations and bad publicity (Sharav).The American public finally learns of the biowarfare experiments being done at Fort Detrick from a report released by the War Department (Goliszek).(1947)Col. E.E. Kirkpatrick of the U.S. Atomic Energy Commission (AEC) issues a top-secret document (707075) dated Jan. 8. In it, he writes that "certain radioactive substances are being prepared for intravenous administration to human subjects as a part of the work of the contract" (Goliszek).A secret AEC document dated April 17 reads, "It is desired that no document be released which refers to experiments with humans that might have an adverse reaction on public opinion or result in legal suits," revealing that the U.S. government was aware of the health risks its nuclear tests posed to military personnel conducting the tests or nearby civilians (Goliszek).The CIA begins studying LSD's potential as a weapon by using military and civilian test subjects for experiments without their consent or even knowledge. Eventually, these LSD studies will evolve into the MKULTRA program in 1953 (Sharav).(1947 - 1953) The U.S. Navy begins Project Chatter to identify and test so-called "truth serums," such as those used by the Soviet Union to interrogate spies. Mescaline and the central nervous system depressant scopolamine are among the many drugs tested on human subjects (Goliszek).(1948)Based on the secret studies performed on Newburgh, N.Y. residents beginning in 1945, Project F researchers publish a report in the August 1948 edition of the Journal of the American Dental Association, detailing fluoride's health dangers. The U.S. Atomic Energy Commission (AEC) quickly censors it for "national security" reasons (Griffiths and Bryson).(1950)(1950 - 1953) The U.S. Army releases chemical clouds over six American and Canadian cities. Residents in Winnipeg, Canada, where a highly toxic chemical called cadmium is dropped, subsequently experience high rates of respiratory illnesses (Cockburn and St. Clair, eds.).In order to determine how susceptible an American city could be to biological attack, the U.S. Navy sprays a cloud of Bacillus globigii bacteria from ships over the San Francisco shoreline. According to monitoring devices situated throughout the city to test the extent of infection, the eight thousand residents of San Francisco inhale five thousand or more bacteria particles, many becoming sick with pneumonia-like symptoms (Goliszek).Dr. Joseph Strokes of the University of Pennsylvania infects 200 female prisoners with viral hepatitis to study the disease (Sharav).Doctors at the Cleveland City Hospital study changes in cerebral blood flow by injecting test subjects with spinal anesthesia, inserting needles in their jugular veins and brachial arteries, tilting their heads down and, after massive blood loss causes paralysis and fainting, measuring their blood pressure. They often perform this experiment multiple times on the same subject (Goliszek).Dr. D. Ewen Cameron, later of MKULTRA infamy due to his 1957 to1964 experiments on Canadians, publishes an article in the British Journal of Physical Medicine, in which he describes experiments that entail forcing schizophrenic patients at Manitoba's Brandon Mental Hospital to lie naked under 15- to 200-watt red lamps for up to eight hours per day. His other experiments include placing mental patients in an electric cage that overheats their internal body temperatures to 103 degrees Fahrenheit, and inducing comas by giving patients large injections of insulin (Goliszek).(1951)The U.S. Army secretly contaminates the Norfolk Naval Supply Center in Virginia and Washington, D.C.'s National Airport with a strain of bacteria chosen because African-Americans were believed to be more susceptible to it than Caucasians. The experiment causes food poisoning, respiratory problems and blood poisoning (Cockburn and St. Clair, eds.).(1951 - 1956) Under contract with the Air Force's School of Aviation Medicine (SAM), the University of Texas M.D. Anderson Cancer Center in Houston begins studying the effects of radiation on cancer patients -- many of them members of minority groups or indigents, according to sources -- in order to determine both radiation's ability to treat cancer and the possible long-term radiation effects of pilots flying nuclear-powered planes. The study lasts until 1956, involving 263 cancer patients. Beginning in 1953, the subjects are required to sign a waiver form, but it still does not meet the informed consent guidelines established by the Wilson memo released that year. The TBI studies themselves would continue at four different institutions -- Baylor University College of Medicine, Memorial Sloan-Kettering Institute for Cancer Research, the U.S. Naval Hospital in Bethesda and the University of Cincinnati College of Medicine -- until 1971 (U.S. Department of Energy, Goliszek).American, Canadian and British military and intelligence officials gather a small group of eminent psychologists to a secret meeting at the Ritz-Carlton Hotel in Montreal about Communist "thought-control techniques." They proposed a top-secret research program on behavior modification -- involving testing drugs, hypnosis, electroshock and lobotomies on humans (Barker).(1952)At the famous Sloan-Kettering Institute, Chester M. Southam injects live cancer cells into prisoners at the Ohio State Prison to study the progression of the disease. Half of the prisoners in this National Institutes of Health-sponsored (NIH) study are black, awakening racial suspicions stemming from Tuskegee, which was also an NIH-sponsored study (Merritte, et al.).(1953 - 1974) The U.S. Atomic Energy Commission (AEC) sponsors iodine studies at the University of Iowa. In the first study, researchers give pregnant women 100 to 200 microcuries of iodine-131 and then study the women's aborted embryos in order to learn at what stage and to what extent radioactive iodine crosses the placental barrier. In the second study, researchers give 12 male and 13 female newborns under 36 hours old and weighing between 5.5 and 8.5 pounds iodine-131 either orally or via intramuscular injection, later measuring the concentration of iodine in the newborns' thyroid glands (Goliszek).